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Nabila BOUATIA-NAJI, PhD

 

 

 Research Associate (CRCN) at the INSERM

French Institute for Health, Basic and Medical Research

 

Year of Birth: 1978

Languages fluent in English, French, Spanish and Arabic

  

Address                                                                                                   

PARCC: PARis Cardiovascular research Centre

Paris Descartes University

Inserm UMR970        

Team 3 director : Genetics to Understand the Pathophysiology of Arterial Disease

56 rue Leblanc F-75015 Paris, FRANCE                                                                  

Phone. +33 (0) 1 53 98 79 95                                                                  

Fax. +33 (0) 1 53 98 79 52

Email. nabila.bouatia-naji(at)inserm.fr

Twitter: @n_bouatianaji 

 

Current Positions

Starting Jan 2019

                          INSERM labeled Team Director (Team 3 PARCC) : Genetics to Understand the Pathophysiology of Arterial Disease

Sept 2017-22 

                          ERC-Team Director Genetics and Functional Genomic Studies of Fibromuscular Dysplasia (FMD) and Spontaneous

                          Coronary Artery Dissscetion (SCAD)

 

Previous Positions

Sept 2011-17

Research Associate and group leader at the Inserm UMR970, Paris Descartes University at the PARCC

I am leading a “Genetics and Functional Genomics of Cardiovascular Disease” group that applies genome-wide association and whole exome sequencing to decipher the genetic basis of common and rare forms of Fibromuscular Dysplasia and Mitral Valve Prolapse.

 

Oct 2009 - August 2011

Research Associate, at the CNRS-UMR8199, Institut Pasteur de Lille.

I conducted several GWAS-based studies individually and within international consortia, mainly within MAGIC (magicinvestigators.org) to understand the genetic basis of quantitative traits related to type 2 diabetes and obesity.

 

Feb 2007 - Sept 2009

Inserm postdoctoral fellowship at the Inserm-U690, Paris, CNRS-UMR8090, Lille.

I performed genetic studies of smallness for gestational age and GWAS to decipher the genetics of fasting glucose and T2D

 

Feb 2006 – January 2007

The British Medical Research Council career development fellowship at the MRC Epidemiology Unit, University of Cambridge, United Kingdom.

I worked on the genetics of weight gain (DiOGenes FP6 project) and resistance to insulin traits in large British population-based cohorts

 

Successful funding applications

 

ERC Starting Grant 2017-2022 (PI)

1,500,000 euros to study the genetics and functional exploration of FMD and SCAD loci and genes 

 

ANR Translational Program (Co-applicant)

130,000 euros to study the functionality of 2 MVP risk loci 

 

Medical Research Foundation (Equipe FRM 2015-2018, Co-applicant) 

175,000 euros to study the molecular basis of genetic association with Fibromuscular Dysplasia

 

Young investigator Funding from the French National Agency (ANR JCJC 2013-2017, PI) 

300,000 euros to study the genetics of Fibromuscular Dysplasia

 

Nord-Pas-De-Calais Region and Government (Contrat-Plan-Etat-Region, PI)

200,000 euros to study the genetics of metabolic traits using metabochip

 

French speaking Diabetes society (ALFEDIAM)/Servier (2008-2009) 

20,000 euros to study the genetics of fasting glucose

 

Awards for research excellence

 

2016         Winner of the International Conference of Human Genetics meeting Young Investigator Award, Kyoto, Japan. Awarding the study on genetics of Fibromuscular Dysplasia.

2014         Finalist of the AHA Functional Genomics and Translational Biology (FGTB) Young Investigator Award for a genetic study of mitral valve prolapse.

2009         French Academy of Sciences: Great achievements in the field of biology of 2009: awarding the study of the genetics of fasting glucose and type 2 diabetes.

 

Post graduate diplomas

 

2011         HDR (Habilitation à diriger des recherches, diploma for PhD supervision and research direction), Faculty of Medicine, Lille 2-Droit-Santé University, Lille, France.

2006         PhD in Human Genetics, -“Genetics of common forms of obesity and type 2 diabetes in French Cohorts”. Faculty of Medicine, Lille 2-Droit-Santé University, Lille, France

2004         University Diploma for post-graduates in “Biostatistics applied to clinical research and epidemiology”

 

Under graduate education

 

2001         DEA (Master Degree equivalent). Sciences and Technology University (USTL), Lille, France.

1999         Licence (BA equivalent) of Molecular and cellular biology at the USTL, Lille, France.

 

Over 12 presentations as an invited speaker in national and international conferences (Mayo Clinic, Mount Sinai Hospital NY, European Society of Cardiology), in addition to peer reviewed abstracts for oral presentations and  posters (AHA, ASHG, ESHG, ICHG, ADA and EASD) 

 

Mentoring of graduate and PhD students

§  Mentoring of 3 PhD students: genetics of Fibromusuclar Dysplasia (2013-2016, 3 articles) and genetics of Mitral Valve Prolapse (2015-2019), functional genomics FMD loci (2018-2021)

§  Co-mentoring of 2 PhD students: genetic epidemiology of fasting glucose (2008-2010, 7 articles) and genetic epidemiology of heart valve disease in West African populations (2015-2018)

§  Mentoring of several research assistants in molecular biology and  statistical genetics.

§  Mentoring of several Master  (medical and scientific students) molecular genetics, statistical genetics from France, USA, Lebanon, Tunisia, Benin. 

 

Teaching activities 

§  Master courses: Master of biology and health science, 2008-2010, Lille 2, 2h/yr; Genomics and statistical genetics Master, Paris 11, (2013-), 2h/yr; Master of genetics common course for MD, PharmD and scientific students, Paris 5, (2015-), 3h/yr, Master of Athersclorosis from mice to human, 2h/yr (2015-)

§  Educational session at Aarhus University about Developmental Programming of Metabolism, Invited by Allan Vaag, DK (2009); SANOFI Symposium, Introduction to genetics of diabetes for MD general practice, Zurich (7h); IPSEN symposium for MD fellows (Genetics of height), Lille (2012).

 

Institutional Responsabilities

§   Member elected of the board of Femmes et Sciences association, to promote scientific careers to girl pupils, support scientific women in leadership 

§   Member elected representing professor and research associates at the scientific council of the Faculty of Medicine, Paris Descartes University (since 2013)

§  Nomination at the early career committee vice chair of the FGTB Council of the AHA (2016-2018) and chair (2018-2020). Mission: to mentor young fellows and participate in reviewing activities for award applications and abstracts scoring of the annual meeting

§  Member of the Steering committee of GWAS consortia (Since 2010): MAGIC (genetics of glucose and Insulin) and CKDGen (Genetics of kidney function). Mission: assess and validate project proposals

2018  Nabila BOUATIA-NAJI  design by  ProGphy - Mentions Légales du site